Detail information of PPI "MPI08616"

IdentifierMPI08616
InteractionDNA fragments  <==>  p53
Role & State        ---
Interaction TypeIT:0000080,effect;
Biological ProcessBP:0016446,mutation; BP:0006915,apoptosis;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference9425920_1, The effect of expression of the p53 gene, in the presence or absence of the p53ser246 mutation (p53*), on ploidization (image cytometry), proliferation (expression of proliferating cell nuclear antigen and radioactive thymidine histoautoradiography), and apoptosis (in situ detection of DNA fragments) is determined in hepatocytes of p53-null and p53*-transgenic mice.