Identifier | MPI47697 |
Interaction | p53 <==> p53 response element |
Role & State | --- |
Interaction Type | IT:0000138,demethylation; IT:0000132,methylation; IT:0000068,transcription; |
Biological Process | BP:0032502,development; |
Biological Function | --- |
Subcelluar Location | SCL:0000785,chromatin; |
Detection Method | DM:0000019,immunoprecipitation; |
Reference | 18573881_3, Chromatin immunoprecipitation (ChIP) and sequential ChIP of developmentally staged liver showed that p53 and LSD1 cooccupy a p53 response element, concomitant with dimethylated histone H3 lysine 4 (H3K4me2) demethylation and postnatal repression of AFP transcription.
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