Detail information of PPI "HPI067203"

IdentifierHPI067203
InteractionSIRT1  <==>  p53
Role & StateRS:0000014,deacetylation;
Interaction TypeIT:0000025,associate; IT:0000364,acetylation; IT:0000308,infect;
Biological ProcessBP:0016032,viral infection; BP:0032502,development;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference19149606_4, SIRT1 and 7 can control myocardial development and resist stress- and aging-associated myocardial dysfunction through the deacetylation of p53 and forkhead box O1 (FoxO1).
Reference21567102_7, Expression of SIRT1 showed significant correlation with gender (p=0.023), serum AFP levels (p=0.030), viral infection (p=0.005) and p53 expression (p0.021).