| Identifier | HPI071807 |
| Interaction | TGF-alpha <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000271,express; |
| Biological Process | BP:0031099,regeneration; |
| Biological Function | --- |
| Subcelluar Location | SCL:0000001,extracellular; SCL:0000002,intracellular; |
| Detection Method | --- |
| Reference | 8666158_3, It has provided insights into the concerted action of extracellular (HGF/SF, TGF-alpha, EGF, TGF-beta) and intracellular factors (c-myc, c-fos, c-jun, p53, c-met, and others) in liver regeneration.
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| Reference | 9755233_10, In patients with colorectal liver metastases, referred for liver surgery, a higher TGF-alpha expression is associated with unfavorable tumor characteristics, whereas p53 and absence of EGFr expression is associated with a better survival after partial liver resection.
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