Identifier | HPI074568 |
Interaction | Taiwanin A <==> p53 |
Role & State | --- |
Interaction Type | IT:0000114,activation; IT:0000252,arrest; |
Biological Process | BP:0006915,apoptosis; BP:0007049,cell cycle; |
Biological Function | --- |
Subcelluar Location | SCL:0000023,microtubule; |
Detection Method | --- |
Reference | 17182066_7, Our results demonstrate that Taiwanin A can act as a new class of microtubule damaging agent, arresting cell cycle progression at mitotic phase and inducing apoptosis through the activation of p53. |