| Identifier | HPI085398 |
| Interaction | c-Abl <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000123,ubiquitination; IT:0000108,reduction; |
| Biological Process | BP:0051168,nuclear export; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 16636310_5, In addition, the observed reductions of nuclear c-Abl in ZD0.2 and ZD0.4 cells to 50% and 60% of ZN cells, respectively, may be a cellular response attempting to normalize nuclear p53 accumulation because nuclear c-Abl is known to down-regulate ubiquitination and nuclear export of p53. |