Detail information of PPI "HPI093175"

IdentifierHPI093175
Interactionheat-shock protein 90  <==>  p53
Role & State        ---
Interaction TypeIT:0000059,binding; IT:0000099,formation; IT:0000123,ubiquitination;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference17363365_8, These results support a model in which MDM2 binding induces a conformational change that is opposed by heat-shock protein 90 and precedes p53 ubiquitination.