Detail information of PPI "HPI098600"

IdentifierHPI098600
InteractionlacZ  <==>  p53
Role & State        ---
Interaction Type        ---
Biological ProcessBP:0016446,mutation;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference10529736_7, It appeared that in the spleen (the major tumor target tissue) of XPA(-/-) and XPA(-/-)/p53(+/-) mice the lacZ mutation frequency was significantly elevated (80-100 x 10(-5)), and was two times higher as found in spleens of B[a]P-treated WT and p53(+/-) mice (P = 0.003).