Identifier | HPI098600 |
Interaction | lacZ <==> p53 |
Role & State | --- |
Interaction Type | --- |
Biological Process | BP:0016446,mutation; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 10529736_7, It appeared that in the spleen (the major tumor target tissue) of XPA(-/-) and XPA(-/-)/p53(+/-) mice the lacZ mutation frequency was significantly elevated (80-100 x 10(-5)), and was two times higher as found in spleens of B[a]P-treated WT and p53(+/-) mice (P = 0.003). |