Detail information of PPI "HPI100640"

IdentifierHPI100640
InteractionmiR-34 family members  <==>  p53
Role & StateRS:0000080,suppressor;
Interaction TypeIT:0000068,transcription; IT:0000242,direct;
Biological ProcessBP:0007049,cell cycle; BP:0007050,cell cycle arrest; BP:0006915,apoptosis;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference20309940_1, The miR-34 family members are direct transcriptional targets of tumor suppressor p53, and loss of miR-34 function can impair p53-mediated cell cycle arrest and apoptosis.