Detail information of PPI "HPI102891"

IdentifierHPI102891
Interactionp21/WAF1  <==>  p53
Role & StateRS:0000074,inhibitor;
Interaction TypeIT:0000077,regulate; IT:0000157,depend; IT:0000078,regulation;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference9699537_1, The cyclin-dependent kinase inhibitor p21/WAF1 is regulated by p5S3-dependent and p53-independent pathways.
Reference9699537_9, Thus, in HCC, expression of p21/WAF1 is in part dependent on p53 status, but a p53-independent pathway also plays a significant role in the regulation of p21/WAF1 expression.