Identifier | HPI103376 |
Interaction | p53 -mediated HBx protein <==> p53 |
Role & State | --- |
Interaction Type | IT:0000078,regulation; |
Biological Process | BP:0016446,mutation; |
Biological Function | --- |
Subcelluar Location | SCL:0000011,endoplasmic reticulum; |
Detection Method | --- |
Reference | 19375220_6, On the other hand, this p53-mediated HBx protein downregulation is impaired by the ablation of p53 nuclear function, which is accomplished by introducing a common feature of HCC, such as the mutation of p53 and endoplasmic reticulum (ER) stress. |