Detail information of PPI "HPI103376"

IdentifierHPI103376
Interactionp53 -mediated HBx protein  <==>  p53
Role & State        ---
Interaction TypeIT:0000078,regulation;
Biological ProcessBP:0016446,mutation;
Biological Function        ---
Subcelluar LocationSCL:0000011,endoplasmic reticulum;
Detection Method        ---
Reference19375220_6, On the other hand, this p53-mediated HBx protein downregulation is impaired by the ablation of p53 nuclear function, which is accomplished by introducing a common feature of HCC, such as the mutation of p53 and endoplasmic reticulum (ER) stress.