Identifier | HPI103612 |
Interaction | p53 family members <==> p53 |
Role & State | --- |
Interaction Type | IT:0000068,transcription; |
Biological Process | BP:0032502,development; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 16203738_3, Transient co-transfection of p53 family members showed that p53 and transactivating (TA)-p73, but not TA-p63, repress endogenous AFP transcription additively or independently. p53-independent functions of p73 are further supported by delayed, p73-associated compensation of AFP repression during development of the p53-null mouse. |