Detail information of PPI "HPI103462"

IdentifierHPI103462
Interactionp53  <==>  HBx proteins
Role & State        ---
Interaction TypeIT:0000068,transcription; IT:0000371,interaction;
Biological ProcessBP:0040007,growth; BP:0016049,cell growth;
Biological Function        ---
Subcelluar Location        ---
Detection MethodDM:0000019,co-immunoprecipitation; DM:0000019,immunoprecipitation;
Reference21438026_3, This was experimentally addressed through co-immunoprecipitation assays examining the interaction between WtHBx and MutHBx proteins with p53, reporter assays determining the impact of the HBx proteins on p53-mediated gene transcription, and clonogenic survival assays evaluating the effect of HBx on cell growth in lines of varying p53-expression status.