Detail information of PPI "HPI103465"

IdentifierHPI103465
Interactionp53  <==>  HCCR-2
Role & State        ---
Interaction TypeIT:0000202,stabilize;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference14691448_3, The level of p53 in HCCR-2 transgenic mice was elevated in most tissues including breast, brain, heart, lung, liver, stomach, kidney, spleen, and lymph node.
Reference14691448_4, We examined whether stabilized p53 is functional in HCCR-2 transgenic mice.
Reference14691448_5, Defective induction of p53 responsive genes including p21WAF1, MDM2, and bax indicates that stabilized p53 in HCCR-2 transgenic mice exists in an inactive form.