| Identifier | HPI103478 |
| Interaction | p53 <==> Hdm2 |
| Role & State | RS:0000002,activity; RS:0000080,suppressor; |
| Interaction Type | IT:0000077,regulate; |
| Biological Process | BP:0001525,angiogenesis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 16432175_1, The activity and stability of the p53 tumor suppressor are regulated by the human homologue of the mouse double minute 2 (Hdm2) oncoprotein.
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| Reference | 19696166_1, The interplay among hypoxia-inducible factor 1-alpha (HIF-1alpha), p53 and human orthologue of murine double minute 2 (Hdm2) has been introduced as a key event in tumor promotion and angiogenesis.
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