Identifier | HPI103489 |
Interaction | p53 <==> IL-6 |
Role & State | RS:0000067,receptor; |
Interaction Type | --- |
Biological Process | BP:0032635,IL-6 production; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 15555057_7, We investigated the role of human IL-6 on p53 null immortalized murine oval cell lines (PIL), finding that they express transcripts for the IL-6 receptor and gp 130, STAT-3 is phosphorylated upon IL-6 stimulation, IL-6 induces IL-6 production, and proliferation is induced by IL-6. |