| Identifier | HPI103501 |
| Interaction | p53 <==> LSD1 |
| Role & State | --- |
| Interaction Type | IT:0000189,target; IT:0000068,transcription; IT:0000026,interact; |
| Biological Process | BP:0032502,development; |
| Biological Function | --- |
| Subcelluar Location | SCL:0000785,chromatin; |
| Detection Method | --- |
| Reference | 18573881_0, p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo.
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| Reference | 18573881_2, We found that p53 directly interacts with lysine-specific demethylase 1 (LSD1) to alter chromatin structure and confer developmental repression of the tumor marker alpha-fetoprotein (AFP).
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