| Identifier | HPI103505 |
| Interaction | p53 <==> MDR1 |
| Role & State | --- |
| Interaction Type | IT:0000114,activation; IT:0000312,cause; IT:0000078,regulation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 9380755_10, Therefore, the p53 inactivation seen in cancers likely leads to selective resistance to chemotherapeutic agents because of up-regulation of MDR1 expression. |