| Identifier | HPI014686 |
| Interaction | CSN5 <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000078,regulation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 21499307_5, The down-regulation of CSN5 was sufficient to interfere with CSN function as evidenced by the accumulation of neddylated Cullin 1 and changes in the protein levels of CSN-controlled substrates SKP2, p53, p27 and nuclear factor-??B, albeit to a different degree depending on the HCC cell line, which could account for the CSN5 knockdown phenotype. |