Detail information of PPI "HPI018515"

IdentifierHPI018515
InteractionCdk  <==>  p53
Role & StateRS:0000074,inhibitor; RS:0000080,suppressor;
Interaction TypeIT:0000128,phosphorylation; IT:0000176,suppress;
Biological ProcessBP:0007049,cell cycle; BP:0000075,cell cycle checkpoint;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference11295047_2, A block of cell cycle checkpoint by dexamethasone and genistein correlates with a selective induction of cyclin-dependent kinase (Cdk) inhibitor p21WAF1/CIP1 in a tumor suppressor p53-independent manner and abolishment of Cdk2 phosphorylation.