Identifier | HPI018515 |
Interaction | Cdk <==> p53 |
Role & State | RS:0000074,inhibitor; RS:0000080,suppressor; |
Interaction Type | IT:0000128,phosphorylation; IT:0000176,suppress; |
Biological Process | BP:0007049,cell cycle; BP:0000075,cell cycle checkpoint; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 11295047_2, A block of cell cycle checkpoint by dexamethasone and genistein correlates with a selective induction of cyclin-dependent kinase (Cdk) inhibitor p21WAF1/CIP1 in a tumor suppressor p53-independent manner and abolishment of Cdk2 phosphorylation.
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