| Identifier | HPI018526 |
| Interaction | Cdk1 <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000078,regulation; IT:0000114,activation; |
| Biological Process | BP:0007049,cell cycle; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 16025114_5, Using the in vivo model of partial hepatectomy to induce synchronous cell cycle entry, we determined that the precise regulation of cyclins D1, E and B1 and of Cdk1 was impaired in Plk4+/- regenerating liver, and p53 activation and p21 and BubR1 expression were suppressed. |