Identifier | HPI019956 |
Interaction | Cytomegalovirus (CMV) <==> p53 |
Role & State | RS:0000080,suppressor; |
Interaction Type | IT:0000176,suppress; |
Biological Process | BP:0040007,growth; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 9436028_10, Results of the study show that whereas universal promoters, such as Cytomegalovirus (CMV) and Rous Sarcoma Virus (RSV) promoter-driven tumor suppressors (e.g. p53, p21, and p16), were effective in inhibiting prostate tumor growth, the advantages of driving the expression of therapeutic toxic genes using a tissue-specific promoter prostate-specific antigen (PSA) and a tumor--but not tissue-specific promoter, osteocalcin (OC), are preferred. |