Detail information of PPI "HPI103530"

IdentifierHPI103530
Interactionp53  <==>  PCNA LI
Role & State        ---
Interaction TypeIT:0000078,regulation; IT:0000271,express;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference17982625_7, Patients with either PTEN down-regulation, p53 (+), or high PCNA LI had shorter survival and higher recurrence rates than patients with intact PTEN expression, p53 (-), or low PCNA LI respectively (P0.05).
Reference7611770_1, Nuclear DNA ploidy analysis, p53 immunohistochemical overexpression and PCNA Labeling Index (PCNA LI) were studied in 80 cases of resected single nodular human hepatocellular carcinoma (HCC) tissue sections.
Reference7611770_10, These results suggest that nuclear DNA ploidy analysis, p53 immunohistochemical overexpression and PCNA LI were useful markers of biological malignant potentials in single nodular human HCCs.
Reference7611770_4, Positive rate of p53 overexpression was significantly higher in patients with HCV-Ab positive and PCNA LI or = 40%.