| Identifier | HPI103547 |
| Interaction | p53 <==> SUZ12 |
| Role & State | --- |
| Interaction Type | IT:0000099,formation; |
| Biological Process | BP:0006281,DNA repair; BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 21480320_4, Knockdown of ZNF198 and SUZ12 by small interfering RNA (siRNA) reduced p53 stability and DNA repair, rescued pX-expressing hepatocytes from DNA damage-induced apoptosis, and increased pX-induced polyploidy and oncogenic transformation, suggesting ZNF198 and SUZ12 have a role in pX-mediated transformation. |