Detail information of PPI "HPI103552"

IdentifierHPI103552
Interactionp53  <==>  TA-p63
Role & State        ---
Interaction TypeIT:0000068,transcription;
Biological ProcessBP:0032502,development;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference16203738_3, Transient co-transfection of p53 family members showed that p53 and transactivating (TA)-p73, but not TA-p63, repress endogenous AFP transcription additively or independently. p53-independent functions of p73 are further supported by delayed, p73-associated compensation of AFP repression during development of the p53-null mouse.