Detail information of PPI "HPI103567"

IdentifierHPI103567
Interactionp53  <==>  U19/EAF2
Role & StateRS:0000002,activity;
Interaction TypeIT:0000176,suppress; IT:0000227,bind;
Biological Process        ---
Biological FunctionBF:0010843,promoter activity;
Subcelluar Location        ---
Detection Method        ---
Reference19826414_4, TSP-1 is reported to be a p53-target gene and p53 is a known binding partner of ELL, which binds to U19/EAF2.
Reference19826414_6, In a TSP-1 promoter-driven luciferase reporter assay, p53 transfection suppressed the TSP-1 promoter activity and U19/EAF2 co-transfection blocked the p53 suppression of TSP-1 promoter.