Detail information of PPI "HPI103600"

IdentifierHPI103600
Interactionp53  <==>  c-myc
Role & StateRS:0000080,suppressor;
Interaction TypeIT:0000176,suppress; IT:0000290,form;
Biological ProcessBP:0006915,apoptosis;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference19273247_4, Mouse embryonic fibroblasts (MEFs) deficient for p53 can be transformed with either c-myc or with rasV12 alone.
Reference7478596_2, Several genes regulating apoptosis have been reported, including p53, one of the tumor suppressor genes, c-myc, one of the proto-oncogenes, and various kinds of Bcl-2 related genes.