Detail information of PPI "HPI103607"

IdentifierHPI103607
Interactionp53  <==>  cyclin-dependent kinase
Role & StateRS:0000074,inhibitor; RS:0000080,suppressor;
Interaction TypeIT:0000371,interaction; IT:0000080,effect;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference12665691_3, Peptide sequencing revealed three proteins whose interaction with p53 had not been previously reported: a cyclin-dependent kinase inhibitor p57/Kip2, a serine/threonine protein phosphatase PP1C, and hemoglobin.
Reference9022146_1, CIP1/WAF1, a critical downstream effector of tumor suppressor p53, encodes a cyclin-dependent kinase inhibitor.