Detail information of PPI "HPI103621"

IdentifierHPI103621
Interactionp53  <==>  heat-shock protein 90
Role & State        ---
Interaction TypeIT:0000059,binding; IT:0000092,degradation; IT:0000099,formation;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference17363365_0, MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation.