Detail information of PPI "HPI103646"

IdentifierHPI103646
Interactionp53  <==>  miR-34
Role & StateRS:0000080,suppressor;
Interaction TypeIT:0000068,transcription;
Biological ProcessBP:0006915,apoptosis; BP:0007049,cell cycle; BP:0007050,cell cycle arrest;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference20309940_1, The miR-34 family members are direct transcriptional targets of tumor suppressor p53, and loss of miR-34 function can impair p53-mediated cell cycle arrest and apoptosis.