Detail information of PPI "HPI103703"

IdentifierHPI103703
Interactionp53  <==>  p14
Role & State        ---
Interaction TypeIT:0000132,methylation; IT:0000153,consist; IT:0000114,activation;
Biological ProcessBP:0016446,mutation;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference11704835_9, Mutations of p53 were found in 30 of 71 HCC (42%), and only one of them harboured p14(ARF) inactivation.
Reference12210082_8, Mutations of p53 were found in 19 of 51 tumours (37%), and four of them (21%) harboured p14(ARF) inactivation.
Reference12845670_7, Alterations of the p53 pathway consisted mostly of p53 mutations or p14(ARF) promoter methylation (20-48%).