| Identifier | HPI103707 |
| Interaction | p53 <==> p21 (Cip1/Waf1 |
| Role & State | --- |
| Interaction Type | IT:0000139,dephosphorylation; IT:0000114,activation; IT:0000128,phosphorylation; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 15004518_0, p53 dephosphorylation and p21(Cip1/Waf1) translocation correlate with caspase-3 activation in TGF-beta1-induced apoptosis of HuH-7 cells.
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| Reference | 15004518_6, This was associated with enhanced p53 dephosphorylation and p21(Cip1/Waf1) expression, which coincided with decreased Cdk2, Cdk4, and cyclin E expression, compared with synchronized G1 cells.
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