Identifier | HPI103714 |
Interaction | p53 <==> p21/WAF1 |
Role & State | --- |
Interaction Type | IT:0000271,express; |
Biological Process | BP:0016446,mutation; BP:0007049,cell cycle; BP:0051318,G1 phase; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 15201954_5, The results showed that p53 over-expression is a reliable marker for mutational modulation of p53 function. p53 was negatively correlated with p21/WAF1 in hepatitis B virus-related HCC (p=0.024, r=-0.432).
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Reference | 15327837_3, In Hep G2, saikosaponin d blocked the progression of cell cycle at G1 phase by inducing p53 expression and further up-regulating p21/WAF1 expression.
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