Detail information of PPI "HPI103719"

IdentifierHPI103719
Interactionp53  <==>  p27
Role & State        ---
Interaction TypeIT:0000025,associate; IT:0000114,activation; IT:0000128,phosphorylation; IT:0000139,dephosphorylation;
Biological Process        ---
Biological Function        ---
Subcelluar LocationSCL:0000010,cytosol;
Detection Method        ---
Reference15004518_9, In conclusion, the results demonstrated that TGF-beta1-induced p53 dephosphorylation is associated with caspase-3 activation, and cytosolic translocation of p21(Cip1/Waf1) and p27(Kip1), resulting in decreased expression of Cdks and cyclins.