| Identifier | HPI103720 |
| Interaction | p53 <==> p28 |
| Role & State | --- |
| Interaction Type | IT:0000080,effect; IT:0000114,activation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | SCL:0000006,cytoplasm; |
| Detection Method | --- |
| Reference | 21691299_6, This effect was observed in p53-deficient cells, suggesting a p53-independent mechanism for the p28(GANK)-mediated activation of ??-catenin. p28(GANK) overexpression also reduced E-cadherin protein levels, leading to increased release of free ??-catenin into the cytoplasm from the cadherin-bound pool. |