| Identifier | HPI103828 |
| Interaction | p53 <==> synthase-2 |
| Role & State | --- |
| Interaction Type | IT:0000068,transcription; IT:0000114,activation; IT:0000124,transactivation; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 9405677_5, The transcriptional transactivation domain of HBx also maps to its C terminus; however, a comparison of the ability of full-length and truncated HBx protein to abrogate p53-induced apoptosis versus transactivate simian virus 40- or human nitric oxide synthase-2 promoter-driven reporter constructs indicates that these two functional properties are distinct and thus may contribute to hepatocarcinogenesis differently. |