Detail information of PPI "HPI112966"

IdentifierHPI112966
Interactionwild-type KLF6  <==>  p53
Role & State        ---
Interaction TypeIT:0000077,regulate;
Biological ProcessBP:0008283,cell proliferation;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference11752579_5, Functional studies confirm that whereas wild-type KLF6 up-regulates p21 (WAF1/CIP1) in a p53-independent manner and significantly reduces cell proliferation, tumor-derived KLF6 mutants do not.