| Identifier | MPI01110 |
| Interaction | AFB1 <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000372,treatment; IT:0000316,induce; |
| Biological Process | BP:0016446,mutation; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 16557586_3, In vitro experiments have also shown that treatment of human liver cells with AFB1 results in p53 mutations.
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| Reference | 16557586_5, However, wild-type mice in which AFB1 alone was used to induce liver cancers have failed to recapitulate p53 mutations, raising the possibility that mouse DNA context may not be appropriate for the generation of AFB1-induced p53 mutations.
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