Identifier | MPI10694 |
Interaction | FTY720 <==> p53 |
Role & State | --- |
Interaction Type | IT:0000139,dephosphorylation; IT:0000128,phosphorylation; |
Biological Process | BP:0006915,apoptosis; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 15297371_10, In conclusion, FTY720 is a novel anticancer agent that induces apoptosis of hepatoma cell lines both in vitro and in vivo through PI3-K-mediated Akt dephosphorylation in a p53-independent manner. |