Identifier | MPI17560 |
Interaction | IRF-1 <==> p53 |
Role & State | --- |
Interaction Type | IT:0000114,activation; IT:0000295,affect; IT:0000078,regulation; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 9472983_6, IRF-1 deficiency did not affect the p53-dependent G1/S arrest after UV irradiation.
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Reference | 9472983_8, However, IRF-1 deficiency produced dysregulation of p53, manifested as increased transactivation of a p53-reporter plasmid in undamaged hepatocytes, and accelerated p53 stabilization after DNA damage.
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