| Identifier | MPI19801 |
| Interaction | LT antigen <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000053,control; IT:0000128,phosphorylation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 9136893_9, We conclude that: (1) Caco-2 cells exert a dominant control against the oncogenic functions of the LT antigen; (2) loss of p53 function is not restrictive for the establishment of polarity and differentiation of the enterocyte lineage; (3) the levels and phosphorylation status of the Rb1 and Rb2 proteins may play important roles in the proliferation and differentiation of normal and neoplastic human colonic mucosa. |