Detail information of PPI "MPI26552"

IdentifierMPI26552
InteractionPin1  <==>  p53
Role & State        ---
Interaction TypeIT:0000114,activation;
Biological ProcessBP:0007049,cell cycle; BP:0007050,cell cycle arrest; BP:0006915,apoptosis;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference17160015_3, Pin1 is required for the timely activation of p53, resulting in apoptosis or cell cycle arrest.
Reference17160015_6, Ablation of Pin1, in addition to p53, accelerated the thymic hyperplasia, but the thymocytes in these Pin1-/-p53-/- mice did not infiltrate other organs.