Detail information of PPI "MPI43657"

IdentifierMPI43657
Interactionisogenic human colon cancer cells  <==>  p53
Role & StateRS:0000074,inhibitor;
Interaction Type        ---
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference15604280_2, Using isogenic human colon cancer cells that differ only in their p53 status, we demonstrate that loss of p53 renders tumor cells relatively resistant to the topoisomerase I inhibitor, irinotecan.