Identifier | MPI44395 |
Interaction | mAb 3 E10 Fv <==> p53 |
Role & State | --- |
Interaction Type | --- |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | SCL:0000002,intracellular; |
Detection Method | --- |
Reference | 17308119_6, These results indicate that Fv-p53 treatment had a profound effect on liver metastasis and represent the first demonstration of effective full-length p53 protein therapy in vivo. mAb 3E10 Fv has significant clinical potential as a mediator of intracellular and intranuclear delivery of p53 for prevention and treatment of cancer metastasis. |