Detail information of PPI "MPI47595"

IdentifierMPI47595
Interactionp53  <==>  Apaf-1
Role & State        ---
Interaction TypeIT:0000078,regulation; IT:0000068,transcription;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference12883670_8, Similarly, we detected a lower Apaf-1 mRNA level in the heart and spleen of p53-/- mice compared with the p53+/+ controls, supporting a transcriptional upregulation of Apaf-1 by p53.