Detail information of PPI "MPI47621"

IdentifierMPI47621
Interactionp53  <==>  Gadd45 gamma
Role & State        ---
Interaction Type        ---
Biological ProcessBP:0008219,cell death;
Biological Function        ---
Subcelluar LocationSCL:0000006,cytoplasm;
Detection Method        ---
Reference17086213_6, Three pro-apoptotic genes, p53, caspase-3 and Gadd45gamma, were downregulated in unr(-/-) ES cells, indicating that Unr, as other cytoplasmic RNA-binding proteins, regulates a complex genetic program, promoting cell death after IR.