| Identifier | MPI47635 |
| Interaction | p53 <==> IRF-1 |
| Role & State | --- |
| Interaction Type | IT:0000078,regulation; |
| Biological Process | BP:0006915,apoptosis; BP:0007050,cell cycle arrest; BP:0006281,DNA repair; BP:0007049,cell cycle; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 9472983_0, Altered DNA repair and dysregulation of p53 in IRF-1 null hepatocytes.
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| Reference | 9472983_2, In different cell types, IRF-1 and p53 can cooperate to produce cell cycle arrest (embryo fibroblasts) or can independently trigger apoptosis (lymphoid cells). p53 may also regulate DNA repair, but there is no information on IRF-1 and repair.
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