Detail information of PPI "MPI47648"

IdentifierMPI47648
Interactionp53  <==>  PI3K
Role & State        ---
Interaction TypeIT:0000130,overexpression;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference18471976_4, Consistent with a role in DNA damage-induced cell-cycle arrest, Prl-3 overexpression induces G(1) arrest downstream of p53 by triggering a PI3K-Akt-activated negative feedback loop.