| Identifier | MPI47692 |
| Interaction | p53 <==> p21 mRNA |
| Role & State | RS:0000002,activity; |
| Interaction Type | IT:0000114,activation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 14985341_5, This activation of the p53 pathway leads to the elevation of p21 mRNA expression, which can be considered an indicator of p53 activity, because ob/ob mice lacking p53 generated by targeting gene disruption exhibited the complete restoration of the p21 elevation to wild type levels. |