Detail information of PPI "HPI029008"

IdentifierHPI029008
InteractionGSK-3  <==>  p53
Role & StateRS:0000074,inhibitor;
Interaction TypeIT:0000202,stabilize; IT:0000078,regulation; IT:0000114,activation;
Biological ProcessBP:0016246,RNA interference;
Biological Function        ---
Subcelluar Location        ---
Detection MethodDM:0000256,rna interference;
Reference18938143_6, GSK-3 inhibitors also stabilized p53 and the down-regulation of p53 by RNA interference abolished the sensitizing effect of lithium on caspase-3 activation.