Identifier | HPI029008 |
Interaction | GSK-3 <==> p53 |
Role & State | RS:0000074,inhibitor; |
Interaction Type | IT:0000202,stabilize; IT:0000078,regulation; IT:0000114,activation; |
Biological Process | BP:0016246,RNA interference; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | DM:0000256,rna interference; |
Reference | 18938143_6, GSK-3 inhibitors also stabilized p53 and the down-regulation of p53 by RNA interference abolished the sensitizing effect of lithium on caspase-3 activation. |